Evaluation of Medication Adherence in Diabetes Mellitus Outpatient in RSUP Fatmawati
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Jun 13, 2024
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Abstract
Patient compliance in carrying out treatment has an important role in the success of treatment. Therefore, researchers need to evaluate compliance with diabetes mellitus medication use. This research is a cross-sectional observational study with prospective data collection. The research was conducted at the Outpatient Clinic of Fatmawati Hospital in September 2023 – November 2023 using the MMAS-8 method on 57 patients. From the results, it is known that there is a significant relationship between level of education, medical therapy, disease complications, behaviour of health workers, comorbidities and Hba1c on the level of patient compliance. The outcome of the study showed patients with a high level of compliance is 42.1% and a low level of compliance is 47.4%. Patients with high compliance had 38.6% polypharmacy in their medication therapy; had disease complications 33.3%; felt that the behaviour of health workers was friendly 42.1%; have no comorbidities 22.8%; and controlled HbA1C 40.3%.
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References
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23. Shruthi, R., Jyothi, R., Pundarikaksha, H., P., Nagesh, G., N., Tushar, T., J. A Study of Medication Compliance in Geriatric Patients with Chronic Illnesses at a Tertiary Care Hospital. J Clin Diagn Res Dec 2016;10(12):FC40-FC43. https://doi.org/10.7860/jcdr/2016/21908.9088
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25. Younis, B., Arshad, R., Yousuf, H., Salman, F., Masood, J., Khursid, S. (2017). Impact of Type 2 Diabetes Mellitus on Quality of Life in People with Diabetes Presenting to a Specialist Diabetes Clinic. Turkish J Med Sci. 47:123-126.
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2. Deischinger, C., Dervic, E., Leutner, M., Kosi-Trebotic, L., Klimek, P., Kautzky, A., & Kautzky-Willer, A. Diabetes mellitus is associated with a higher risk for major depressive disorder in women than in men. BMJ open diabetes research & care, 2020. 8(1), e001430. https://doi.org/10.1136/bmjdrc-2020-001430
3. Dias, A., Costa, F., Neves, S., J., F. The 8-item Morisky Medication Adherence Scale : Validation of a Brazilian – Portuguese version in Hypertensive Adults. Research in Social and Administrative Pharmacy. 2013. 10(3):554-61. https://doi.org/10.1016/j.sapharm.2013.10.006
4. Doya, I., F., Yahaya, J., J., Ngaiza, A., I., Bintabara, D. Low medication adherence and its associated factors among patients with type 2 diabetes mellitus attending Amana Hospital in Dar es Salaam, Tanzania: a cross-sectional study, International Health, 2023.ihad042, https://doi.org/10.1093/inthealth/ihad042
5. Eliza, D., Syafhan, N., F., Andrajati, R., Fitriani, S., W. Medicaion Adherence, Glycemic Control and Quality of Life in Patients with Type 2 Diabetes Mellitus : a cross – sectional study. J Sains Farm Klin. 2023. 10(1) : 21 – 27. DOI: 10.25077/jsfk.10.1.21-27.2023
6. Elsous, A., Radwan, M., Al-Sharif, H., & Abu Mustafa, A. Medications Adherence and Associated Factors among Patients with Type 2 Diabetes Mellitus in the Gaza Strip, Palestine. Frontiers in endocrinology, 2017.8,100. https://doi.org/10.3389/fendo.2017.00100
7. Erawatyningsih, dkk. Faktor-Faktor Yang Mempengaruhi Ketidakpatuhan Berobat Pada Penderita Tuberkulosis Paru di Wilayah Kerja Puskesmas Dompu Barat Kecamatan Woja Kabupaten Dompu Provinsi NTB, Berita Kedokteran Masyarakat. 2009. Volume 25 No. 3.
8. Eyth, E., Naik, R. (2023). Hemoglobin A1C. StatPearls Publishing.
9. Grant, W., R., Devita, N., G., Singer, D., E., Meigs, J., B. Polypharmacy and medication adherence in patients with type 2 diabetes. Diabetes Care. May 2003; 26(5):1408-12. doi: 10.2337/diacare.26.5.1408.
10. Horii T, Momo K, Yasu T, Kabeya Y, Atsuda K. Determination of factors affecting medication adherence in type 2 diabetes mellitus patients using a nationwide claim-based database in Japan. PLoS One. Oct 2019; 8;14(10):e0223431. doi: 10.1371/journal.pone.0223431. PMID: 31593574; PMCID: PMC6782087.
11. Iswanto, (2004). Beberapa Faktor yang Berhubungan dengan Kadar Gula Darah Puasa Pasien Rawat Jalan Diabetes Melitus Tipe 2 Pukesmas Pasar Minggu. Skripsi. Jakarta. FKM UI.
12. Janezic, A., Locatelli, I., Kos, M. Criterion Validity of 8 – item Morisky Medication Adherence Scale in Patient with Asthma. PLos One. 2017. 12(11). https://doi.org/10.1371%2Fjournal.pone.0187835
13. Jimmy, B., Jose, J. Patient Medication Adherence : Measures in Daily Practice. Oman Med J. 2011; 26(3): 155-9
14. Kementerian Kesehatan RI. (2020). Infodatin. Pusat Data dan Informasi Kementerian Kesehatan RI. Tetap Produktif, Cegah, dan Atasi Diabetes Melitus.
15. Masnoon, N., Shakib, S., Kalisch-Ellett, L. et al. What is polypharmacy? A systematic review of definitions. BMC Geriatr; 2017, 230. https://doi.org/10.1186/s12877-017-0621-2
16. Mokolamban, C., Wiyono, W.I., Mpilla, D.A. “Kepatuhan Minum Obat pada Pasien Diabetes Melitus Tipe 2 Disertai Hipertensi dengan Menggunakan Metode MMAS-8.” Pharmacon, 2018; 7(4).
17. Moon, S.,J., Lee, W.,Y., Hwang, J.,S., Hong, Y.,P., Morisky, D., E. Accuracy of a Screening Tool for Medication Adherence: A Systematic Review and Meta-analysis of the Morisky Medication Adherence Scale-8. PLos One 2018; 13(4). https://doi.org/10.1371/journal.pone.0196138
18. Morisky, D., E., Ang, A., Krousel-Wood, M., Ward, H., J. Predictive Validity of a Medication Adherence Measure in an Outpatient Setting. The Journal of Clinical Hypertension. 2008; 10(5): 348-354
19. Perkumpulan Endokrinologi Indonesia (Perkeni). (2021). Pedoman Pengelolaan dan Pencegahan Diabetes Melitus Tipe 2 Dewasa di Indonesia. Jakarta : PB Perkeni
20. Perkumpulan Edukator Diabetes Indonesia (PEDI). (2023). Penatalaksanaan Diabetes Melitus Panduan Bagi Edukator Diabetes. Jakarta.
21. Ponnusankar S, Surulivelrajan M, Anandamoorthy N, Suresh B. Assessment of impact of medication counseling on patients’ medication knowledge and compliance in an outpatient clinic in South India. Patient Educ and Couns. 2004; 54(1):55–60. doi: 10.1016/S0738- 3991(03)00193-9
22. Scarton, L., Nelson, T., Yao, Y., DeVaughan-Circles, A., Legaspi, A. B., Donahoo, W. T., Segal, R., Goins, R. T., Manson, S. M., & Wilkie, D. J. Association of Medication Adherence With HbA1c Control Among American Indian Adults With Type 2 Diabetes Using Tribal Health Services. Diabetes care, 2023; 46(6), 1245–1251. https://doi.org/10.2337/dc22-1885
23. Shruthi, R., Jyothi, R., Pundarikaksha, H., P., Nagesh, G., N., Tushar, T., J. A Study of Medication Compliance in Geriatric Patients with Chronic Illnesses at a Tertiary Care Hospital. J Clin Diagn Res Dec 2016;10(12):FC40-FC43. https://doi.org/10.7860/jcdr/2016/21908.9088
24. Soraya, I., A., Sauriasari, R., Prawiroharjo, P., Risni, H., W. The Association between Adherence to Oral Antihyperglycemic Agent and HbA1c Level, Pharmaceutical Sciences and Research. 2022; Vol. 9: No. 2, Article 4. DOI: 10.7454/psr.v9i2.1260
25. Younis, B., Arshad, R., Yousuf, H., Salman, F., Masood, J., Khursid, S. (2017). Impact of Type 2 Diabetes Mellitus on Quality of Life in People with Diabetes Presenting to a Specialist Diabetes Clinic. Turkish J Med Sci. 47:123-126.
26. World Health Organization. (2022).